Immunological dynamics after subcutaneous immunization with a squalene‐based oil‐in‐water adjuvant
نویسندگان
چکیده
منابع مشابه
GM2-KLH conjugate vaccine: increased immunogenicity in melanoma patients after administration with immunological adjuvant QS-21.
The cell surface gangliosides GM2, GD2, and GD3 are often overexpressed in malignant melanoma. We have shown previously that immunization of melanoma patients with GM2 and Bacillus Calmette-Guérin induced an IgM antibody response in most patients and that patients with high titer GM2 antibodies showed increased survival. As is commonly seen with carbohydrate antigens (which are T independent), ...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2020
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.202000848r